Dr. Brouse on Telomeres & Vivix
Without telomeres, the main part of the chromosome the part with genes essential for life would get shorter each time a cell divides. So telomeres allow cells to divide without losing genes by a protective enzyme called telomerease. . Cell division is necessary for growing new skin, blood, bone, and other cells which when speeded up by stress and poor nutrition become vulnerable to rapid aging and telomere shortening. This telomere shorteniong seems to play a role in activating cancer cells
Laboratory studies show that both Vivix and Vivix Kosher (with pomegranate) key ingredients protect and repair DNA. In a clinical study, key ingredients were shown to blunt the inflammatory response that normally occurs from an unhealthy meal, which over time can lead to cellular aging.*
Without telomeres, chromosome ends could fuse together and corrupt the cell’s genetic blueprint, possibly causing malfunction, cancer, or cell death. Because broken DNA is dangerous, a cell has the ability to sense and repair chromosome damage.
Without telomeres, the ends of chromosomes would look like broken DNA, and the cell would try to fix something that wasn’t broken. That also would make them stop dividing and eventually die. This is the aging process that is brought about by other factors besides telomere shortening. Oxidative stress, high circulating blood sugar and cumulative cell damage all contribute to this process.
Telomeres – More Important In Cancer Prevention Than We Thought: Cancer Connection
Many cancers have shortened telomeres, including pancreatic, bone, prostate, bladder, lung, kidney, and head and neck. Measuring telomerase may be a way to detect other types of cancer as well. And if scientists can learn how to stop telomerase, they might be able to fight cancer by making cancer cells age and die. In one experiment, researchers blocked telomerase activity in human breast and prostate cancer cells growing in the laboratory, prompting the tumor cells to die. But there are risks. Blocking telomerase.
Progressive telomere shortening occurs with each cell division up to a point termed “replicative senescence” in most mature human cells72. Basic biology studies have established that telomere shortening is a fundamental feature of dividing cells and directly related to the age of the cell lineage, and that telomere crisis in the present of defective cell-cycle control can lead to chromosomal instability and a malignant phenotype73. The dysfunctional telomeres will result in chromosomal fusions, continuous “breakage-fusion-bridge” cycles, derived chromosome imbalances, gene amplifications, and ultimately the generation of complex non-reciprocal translocations, a hallmark feature of adult solid tumors and genomic instability in general74. At the population level, the high incidence of cancer has prompted that shortening of telomeres promotes tumor development and several studies have found that patients with shorter telomeres in peripheral blood cells have a higher risk of developing carcinomas75.
Nobel Prize in Medicine
Shaklee is collaborating with Nobel Laureate, Elizabeth Blackburn of the University of California, San Francisco, who was named the 2009 Nobel Prize winner in medicine for discovering how chromosomes are protected by telomeres and the enzyme telomerase.
In the Shaklee Telomere Research Landmark Study II, this study on DNA and longevity and includes 107 Shaklee participants who have been taking Shaklee (Vitalizer, Vivix and Cinch) for approximately five years, as well as a group of non-supplement users.
Preliminary results of the study are very impressive. Shaklee Vivix and Cinch users had 40% less shrinkage of their telomers than the general public. That means that a 55 year old man or woman had the telomeres of a 35 year old after using these for 5 years. There is more research to come!